在我的数据上运行coxph时收到错误消息。你以前有没有人见过这个？
coxph(Surv(OS,Survival_dead0_alive1)~.,data=data.frame(Bind))
Error in fitter(X, Y, strats, offset, init, control, weights = weights, :
NA/NaN/Inf in foreign function call (arg 6)
In addition: Warning message:
In fitter(X, Y, strats, offset, init, control, weights = weights, :
Ran out of iterations and did not converge
我的数据：
> head(Bind)
hsa-let-7a-5p hsa-let-7b-5p hsa-let-7f-5p hsa-let-7g-5p hsa-let-7i-5p hsa-miR-101-3p hsa-miR-103a-3p
020 8.525737 9.077023 8.380155 7.734305 9.724084 8.505507 9.952546
045 11.885240 10.680675 12.909627 9.659705 11.684750 9.501075 11.060350
080 11.922765 9.709317 12.937002 9.608698 11.027545 8.918902 10.198448
082 10.522788 9.800196 11.019010 9.017653 10.608756 9.116801 10.981711
084 14.398983 13.917347 15.950312 13.643770 14.849673 19.106340 16.381978
086 12.991248 10.526353 13.891862 10.216253 11.871303 10.267358 12.060968
hsa-miR-106b-3p hsa-miR-107 hsa-miR-10a-5p hsa-miR-10b-5p hsa-miR-126-3p hsa-miR-126-5p hsa-miR-1307-5p
020 8.736831 9.913751 8.785006 9.509614 6.160457 9.568709 6.472602
045 9.669884 10.600395 12.072752 12.616410 9.841329 12.199432 9.835345
080 8.676124 9.745139 13.143389 14.097870 9.780005 12.678141 9.981547
082 9.479583 10.787869 11.212550 12.326868 7.600882 9.797073 8.937480
084 10.072361 16.327778 21.089233 16.415726 10.885272 15.550348 15.349871
086 9.722471 11.788772 12.815745 13.895031 9.928474 11.956818 10.526353
hsa-miR-130a-3p hsa-miR-140-3p hsa-miR-141-3p hsa-miR-142-5p hsa-miR-143-3p hsa-miR-144-3p hsa-miR-144-5p
020 6.993426 7.063975 2.726202 10.83548 8.177073 6.984873 5.875895
045 8.700323 8.623106 4.258602 11.72496 11.017748 8.352795 7.199350
080 8.410844 7.129067 7.687576 11.53991 9.249907 8.753803 8.505378
082 7.368333 8.589622 3.899788 11.20649 9.622052 8.410481 7.349408
084 13.824029 9.881256 5.942495 12.49186 16.496929 12.346393 10.387328
086 8.748585 8.646370 5.992389 11.39576 9.960052 9.374619 9.451418
hsa-miR-146b-5p hsa-miR-148a-3p hsa-miR-151a-3p hsa-miR-15a-5p hsa-miR-16-2-3p hsa-miR-16-5p hsa-miR-181a-5p
020 6.825487 8.935624 9.495543 10.02602 8.794871 13.70308 9.505791
045 7.506878 11.608944 12.364735 10.58655 9.783405 14.09747 12.248791
080 6.461902 11.315771 11.297933 9.99134 8.983739 12.79753 13.281242
082 5.765382 11.144908 9.497258 10.51729 9.056027 13.58097 12.631773
084 10.525156 25.006534 13.430802 16.22535 10.185384 17.70031 16.908886
086 6.438835 11.889882 11.091509 11.33448 9.552341 13.50666 13.578251
hsa-miR-182-5p hsa-miR-186-5p hsa-miR-191-5p hsa-miR-192-5p hsa-miR-199a-3p hsa-miR-199b-3p hsa-miR-19a-3p
020 9.554027 10.55887 10.57660 10.059605 5.331217 5.331217 5.473092
045 10.017655 11.68161 13.00958 10.644459 10.574318 10.574318 6.284569
080 9.836127 11.09218 12.47866 11.009756 9.745139 9.745139 5.932696
082 10.211428 10.43197 11.69112 10.866778 8.361732 8.361732 5.938032
084 12.149268 15.05111 12.28892 22.162546 16.668760 16.668760 10.145723
086 10.300424 11.32269 12.31837 9.495561 10.011156 10.011156 6.305182
hsa-miR-19b-3p hsa-miR-21-5p hsa-miR-22-3p hsa-miR-25-3p hsa-miR-26a-5p hsa-miR-26b-5p hsa-miR-27a-3p
020 7.080042 9.055677 12.95556 13.10529 9.069946 6.581722 6.882323
045 7.887126 12.328800 15.40046 12.92344 12.977058 9.321807 10.074278
080 6.942131 12.833538 14.09914 11.58682 13.133720 9.456343 9.879351
082 7.290994 10.615609 14.03497 12.77837 11.096663 7.799290 9.627379
084 12.074954 21.150996 26.76700 16.02596 15.937430 12.473736 14.947538
086 7.750132 12.580098 14.72288 12.65702 12.772796 9.466287 10.491131
hsa-miR-27b-3p hsa-miR-29a-3p hsa-miR-30a-5p hsa-miR-30c-5p hsa-miR-30d-5p hsa-miR-30e-5p hsa-miR-320a hsa-miR-320b
020 9.222262 5.360835 7.503475 5.189058 11.73659 10.92572 7.714683 6.111557
045 12.030654 8.060408 9.922490 10.542361 13.85970 12.91382 10.349932 9.625221
080 11.618125 8.753803 10.747875 10.231342 12.67439 11.65418 10.347811 9.802744
082 10.319820 7.978314 9.475624 9.192182 12.14658 11.34347 9.547060 8.036919
084 23.451162 17.093151 18.631805 8.413819 16.01589 17.65584 18.486646 16.166823
086 10.875653 8.103078 10.476791 10.659025 13.05021 11.82513 11.141786 10.233496
hsa-miR-3615 hsa-miR-375 hsa-miR-378a-3p hsa-miR-423-3p hsa-miR-423-5p hsa-miR-425-5p hsa-miR-451a hsa-miR-484
020 7.480079 6.491425 6.215312 8.705659 13.22919 9.868943 13.51664 10.042707
045 9.027042 8.174936 9.268583 12.656559 14.89358 10.940546 13.76140 11.108842
080 8.077681 9.825093 8.728419 11.246651 14.47793 9.931447 12.62325 9.900439
082 8.649305 7.910777 9.034232 10.986268 14.30074 10.004025 14.28673 10.770453
084 5.716977 14.013445 19.926417 17.625759 21.80929 8.468569 16.24687 11.286335
086 9.037216 6.673159 10.340692 11.833391 15.80876 9.874213 14.17999 11.132777
hsa-miR-486-3p hsa-miR-486-5p hsa-miR-584-5p hsa-miR-660-5p hsa-miR-92a-3p hsa-miR-92b-3p hsa-miR-93-5p
020 7.593128 17.87764 6.936818 6.245665 14.81484 8.272820 9.909526
045 9.512490 17.73956 9.656295 7.049662 16.61683 9.286554 10.674161
080 8.077681 16.46870 9.065472 6.723940 15.73787 10.130069 9.004656
082 9.152502 17.92071 8.348126 6.928074 16.21035 7.917058 9.963153
084 5.750738 19.70099 7.238084 12.881830 20.27929 4.620864 11.917808
086 8.319596 18.18648 10.145087 7.937656 17.02111 8.698406 10.189986
hsa-miR-99a-5p OS Survival_dead0_alive1
020 5.331217 6 1
045 7.072067 11 1
080 6.837582 29 0
082 6.762251 2 0
084 15.891079 40 1
086 5.992389 40 1